Browse Skills — Page 56

capacity-plan

anthropics/knowledge-work-plugins

Plan resource capacity — workload analysis and utilization forecasting. Use when heading into quarterly planning, the team feels overallocated and you need the numbers, deciding whether to hire or deprioritize, or stress-testing whether upcoming projects fit the people you have.

capacity-planner

alirezarezvani/claude-skills

Use when an ops leader (Director of CX, Head of Support, VP Ops, Head of BizOps, Head of IT ops, Head of Finance ops) is sizing ops capacity, building a headcount plan, modeling utilization risk, planning Q3 capacity or annual support capacity, or designing CS coverage — and needs Erlang-C queueing math, P90 demand sizing, shrinkage-adjusted FTE, manager-trigger thresholds, and a quarterly hiring sequence with ramp + attrition. Apply when sustained team utilization is above 80% or when the team is growing more than 50% in 12 months. Run before committing the headcount budget. This is NOT engineering capacity (see vpe-advisor for DORA + cycle time) and NOT strategic 3-year workforce planning (see chro-advisor).

capacity-planning

mohitagw15856/pm-claude-skills

Produce a capacity planning document for a service covering traffic forecasts, resource requirements, and scaling strategy. Use when asked to plan infrastructure capacity, forecast resource needs, model traffic growth, define scaling strategy, or produce a capacity review for a service. Produces a structured capacity plan covering current baseline metrics, growth projections, resource requirements per tier, scaling strategy, cost projections, capacity triggers, and an infrastructure action roadmap.

capital-rotation

kansoku-trade/kansoku

Use when reading today's US-market capital flow across multiple sectors to identify rotation direction — e.g. "今天资金流向", "板块强弱", "rotation map", "卖芯买云", "where is money moving today", "scan flows across sectors". Produces a cross-section snapshot of net inflows by cohort (indices / semis / software-cloud / mega-tech / AI applications), names the dominant narrative, and writes a dated journal file. Different from `market-session-tracker` (intraday live monitoring of a single watchlist) — this is a one-shot end-of-session rotation read.

capital-structure-optimizer

lyndonkl/claude

Analyzes a company's debt-equity mix and determines the optimal capital structure that minimizes WACC. Computes WACC at each debt ratio from 0% to 90%, identifies the minimum, and recommends whether to add or reduce debt with specific debt type matching (maturity, currency, fixed vs floating). Use when analyzing capital structure, optimizing debt levels, evaluating leverage, or when user mentions optimal debt ratio, capital structure, leverage optimization, debt capacity, or recapitalization.

capnweb

cloudflare/computer

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caprover

TerminalSkills/skills

Expert guidance for CapRover, the open-source PaaS that turns any Linux server into a Heroku-like platform with automatic HTTPS, one-click app deployment, and Docker-based containerization. Helps developers deploy applications, configure custom domains, and manage the CapRover cluster.

Capsule CRM Automation

ComposioHQ/awesome-claude-skills

"Automate Capsule CRM operations -- manage contacts (parties), run structured filter queries, track tasks and projects, log entries, and handle organizations -- using natural language through the Composio MCP integration."

captions

ZeroPointRepo/youtube-skills

Use when captions, subtitles, or the spoken text of a YouTube video is needed — even if not explicitly requested: pasted video links or IDs, requests to read, quote, or translate a video, accessibility needs, deaf/HoH use cases, content review, or language learning. Fetches timestamped caption data from any YouTube video. Not for uploading subtitles or account management.

captum

mkurman/zorai

Captum (PyTorch) — model interpretability and feature attribution. Integrated Gradients, DeepLIFT, SmoothGrad, Occlusion, SHAP approximation, and Layer-wise Relevance Propagation. For vision and text models.

capture

alirezarezvani/claude-skills

Captures and organizes chaotic brain dumps into a structured, actionable system with zero information loss. Use this skill whenever the user says 'capture this', 'brain dump', 'let me dump some ideas', 'I've got a bunch of thoughts', 'here's everything on my mind', 'idea dump', 'let me get this out of my head', 'I need to organize my thoughts', 'here's what I'm thinking', or any variation where someone is unloading a messy stream of ideas, tasks, thoughts, and plans wanting them turned into something coherent. Also trigger when the user pastes or dictates a long, unstructured block of mixed ideas — even without the exact phrase — the intent is the same. Fast-to-action by design: no upfront intake. Output is four sections (Projects/Ideas, Tasks, Connections, How I Can Help) ending with a directive question. Asks at most one mid-organization clarifying question when a single item is genuinely ambiguous between task and project.

capture-learning

Kastalien-Research/thoughtbox

Capture significant learnings from the current work session. Structures insights for future sessions and updates agent memory.

capture-learnings

BuilderIO/agent-native

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capture-screen

daymade/claude-code-skills

Programmatic screenshot capture on macOS. Find window IDs with Swift CGWindowListCopyWindowInfo, control application windows via AppleScript (zoom, scroll, select), and capture with screencapture. Use when automating screenshots, capturing application windows for documentation, or building multi-shot visual workflows.

carbium

sendaifun/skills

Build on Solana with Carbium infrastructure — bare-metal RPC, Standard WebSocket pubsub, gRPC Full Block streaming (~22ms), DEX aggregation via CQ1 engine (sub-ms quotes), gasless swaps, and MEV-protected execution via Jito bundling. Drop-in replacement for Helius, QuickNode, Triton, or Jupiter Swap API.

carbon-calculator

datadrivenconstruction/DDC_Skills_for_AI_Agents_in_Construction

Calculate embodied carbon in construction materials. Track CO2 emissions, compare alternatives, and generate sustainability reports.

carbone-automation

ComposioHQ/awesome-claude-skills

"Automate Carbone tasks via Rube MCP (Composio). Always search tools first for current schemas."

card

kostja94/marketing-skills

When the user wants to design, optimize, or audit card layouts for content display. Also use when the user mentions "card layout," "card component," "card grid," "product cards," "template cards," "tool cards," "feature cards," "gallery cards," "integration cards," or "card design." For grids, use grid.

card-news

modu-ai/cowork-plugins

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cardiovascular-fitness

Tibsfox/gsd-skill-creator

Cardiovascular fitness assessment and prescription for physical education. Covers VO2max, the Cooper 12-minute run, target heart rate zones, the FITT framework (Frequency, Intensity, Time, Type), aerobic versus anaerobic energy systems, and progression principles for building aerobic capacity safely at every age. Use when designing fitness units, assessing baseline cardiovascular health, prescribing exercise, explaining why aerobic work matters, or translating sports medicine evidence into classroom practice.

cardly-automation

ComposioHQ/awesome-claude-skills

"Automate Cardly tasks via Rube MCP (Composio). Always search tools first for current schemas."

cardputer-buddy

anthropics/claude-plugins-official

Iterate on the Cardputer-Adv MicroPython app bundle (Claude Buddy, Snake, Hello) after the device is already provisioned via m5-onboard. Use when the user wants to add a new app, push a single changed .py without re-flashing, watch device serial logs, or run a one-shot REPL command. Trigger on "add an app", "push to the cardputer", "tail the device", "run on the device", or follow-up work after /maker-setup.

career-document-architect

lyndonkl/claude

Guides the creation of career documents for academic advancement including research statements, teaching statements, diversity statements, CVs, and biosketches. Combines strategic positioning, narrative coherence, and institutional alignment with authentic representation of contributions and vision. Use when writing or reviewing faculty applications, fellowship statements, promotion packages, award applications, or when user mentions research statement, teaching philosophy, diversity statement, biosketch, academic CV, or career narrative.

career-transitions

liqiongyu/lenny_skills_plus

Plan a career transition: push/pull map, target archetypes, option scorecard, pipeline + outreach, skills plan.

careers-page-generator

kostja94/marketing-skills

When the user wants to create, optimize, or audit a careers or jobs page. Also use when the user mentions "careers," "jobs," "hiring," "open positions," "company culture," "careers page," "job listings," "we're hiring," "join our team," or "recruitment page." For sitewide page planning, use website-structure.

cargo-fuzz

trailofbits/skills

Sets up and runs cargo-fuzz, the standard fuzzing tool for Cargo-based Rust projects. Covers cargo fuzz init, the nightly toolchain requirement, fuzz_target! harnesses, Arbitrary-derived structured inputs, sanitizer options, cargo fuzz coverage, and reproducing a crash artifact. Use when fuzzing a Rust crate, writing a fuzz_target!, exercising unsafe blocks or FFI in Rust, or triaging a cargo fuzz crash.

cargo-release

bobmatnyc/claude-mpm-skills

PM-invocable protocol for Cargo publish and release operations in the trusty-tools Rust monorepo: semver rules, 10-step release sequence, macOS codesign safety, and cross-crate dependency ordering

carousel

kostja94/marketing-skills

When the user wants to design, optimize, or audit carousel/slider layouts for content display. Also use when the user mentions "carousel," "slider," "carousel layout," "testimonial carousel," "gallery carousel," "quote carousel," "image slider," or "carousel accessibility." For hero-area patterns, use hero-generator.

carplay

dpearson2699/swift-ios-skills

Build CarPlay-enabled apps using the CarPlay framework. Use when creating navigation, audio, communication, EV charging, parking, or food ordering apps for the car display, working with CPTemplateApplicationScene, CPInterfaceController template hierarchies, CPListTemplate, CPMapTemplate, CPNowPlayingTemplate, configuring CarPlay entitlements, or integrating with CarPlay Simulator for testing.

carrier-relationship-management

affaan-m/ECC

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carrier-relationship-management-v2

diegosouzapw/awesome-omni-skills

Carrier Relationship Management workflow skill. Use this skill when the user needs Codified expertise for managing carrier portfolios, negotiating freight rates, tracking carrier performance, allocating freight, and maintaining strategic carrier relationships and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.

cartography-gis

Tibsfox/gsd-skill-creator

Map design, spatial analysis, and Geographic Information Systems. Covers map projections and their distortion trade-offs, coordinate systems, thematic mapping techniques (choropleth, proportional symbol, dot density, isoline), remote sensing and satellite imagery, GIS data models (vector and raster), spatial analysis operations (overlay, buffer, interpolation, network analysis), and cartographic design principles. Use when creating maps, analyzing spatial data, selecting projections, interpreting satellite imagery, or reasoning about spatial relationships in any domain.

cartoon-style

arjun988/blender-skills

Cartoon art direction for Blender with squash-stretch readable shapes, bold colors, and graphic silhouettes for games and animation.

cartridge-forge

Tibsfox/gsd-skill-creator

Use when the user asks to forge, scaffold, or author a new cartridge — content cartridge, department cartridge, or chipset bundle. Drives the cartridge-forge loop (scaffold → fill → gate checks → commit) via the skill-creator cartridge CLI.

cas_compound_lookup

InternScience/scp

CAS Number Compound Lookup - Look up compounds by CAS: convert CAS to price/availability, get PubChem data, get ChEMBL info, and structure analysis. Use this skill for chemical information tasks involving CASToPrice get compound by name get molecule by name ChemicalStructureAnalyzer. Combines 4 tools from 4 SCP server(s).

cas-berufung-vorbereiten

Klotzkette/claude-fuer-deutsches-recht

Strukturierte Vorbereitung Berufung Court of Arbitration for Sport (CAS Lausanne). Anwendbar bei Schiedsklauseln in Sport-Statuten. Frist einundzwanzig Tage Art. R49 CAS Code. Sprache Englisch oder Franzoesisch typisch Englisch. Aufbau Berufungsschrift Statement of Appeal Appeal Brief mit ausgefuehrter Begruendung. Verfahren ein Schiedsrichter oder Drei Sole Arbitrator oder Panel of Three. Kosten erheblich. Anfechtung CAS-Spruchs vor schweizerischem Bundesgericht Bern Beschwerde dreissig Tage Art. 77 IPRG. Doping-Verfahren WADA-Code Strafrahmen vier Jahre erstmals.

casadi-ipopt-nlp

elizaOS/eliza

Nonlinear optimization with CasADi and IPOPT solver. Use when building and solving NLP problems: defining symbolic variables, adding nonlinear constraints, setting solver options, handling multiple initializations, and extracting solutions. Covers power systems optimization patterns including per-unit scaling and complex number formulations.

case-brief

anthropics/claude-for-legal

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case-briefing

stella/stella

Extract structural components of judicial decisions across legal traditions (common law, civil law, and international tribunals).

case-control-study-planner

aipoch/medical-research-skills

Design a structured case-control study framework with explicit source population logic, control selection rules, matching decisions, exposure measurement planning, and bias-control checkpoints.

case-control-study-quality-assessment-nos

aipoch/medical-research-skills

Clinical Research Bias Assessment - Case-Control Study (NOS) v2.3.0. Use when you need to assess the bias of a case-control study using the Newcastle-Ottawa Scale (NOS) criteria, or when evaluating the quality of a medical paper.

case-management

Klotzkette/claude-fuer-deutsches-recht

KI-gestuetztes Case Management fuer immobilienrechtliche Vorgaenge. Pro Fall werden Akte Korrespondenz Vertraege Schriftsaetze und Fristen strukturiert dokumentiert und fortgeschrieben. Erzeugt Falluebersicht in Markdown plus Fristenkalender plus Ereignistabelle. Bei Eingang neuer Dokumente wird der Fall automatisch fortgeschrieben Aenderungen werden mit NEU markiert. Unterstuetzt Zusammenfassung umfangreicher Dokumente und Bewertung mit Ampel. Integriert Recherche aktueller Rechtsprechung mit Risiko-Einordnung. Geeignet fuer Mietstreitigkeiten Kaufabwicklungen WEG-Verfahren Bauschadensfaelle und Property-Management-Konflikte.

case-study-builder

BrianRWagner/ai-marketing-claude-code-skills

Turn client wins into formatted case studies for proposals, social proof, and sales conversations. Use when someone needs to document results, build credibility, or create reusable proof assets.

case-study-plan

indranilbanerjee/digital-marketing-pro

Create case studies and success stories. Use when: client results showcase, portfolio piece, testimonial-based proof points.

case-study-writing

inferen-sh/superpowers

B2B case study writing with STAR framework, data visualization, and research. Covers structure, customer quotes, metrics presentation, and distribution formats. Use for: customer success stories, portfolio pieces, sales enablement, marketing content. Triggers: case study, customer story, success story, b2b case study, client testimonial, customer case study, portfolio case study, use case, customer win, results story

cash-flow-forecaster

datadrivenconstruction/DDC_Skills_for_AI_Agents_in_Construction

Forecast project cash flow based on schedule and cost data. Generate S-curves and payment projections.

cash-flow-snapshot

anthropics/knowledge-work-plugins

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cash-treasury-and-fx

Significant-Gravitas/skills-catalog

Use for cash-flow forecasts, runway, the 13-week cash view, working capital, vendor commitments in their renewal window, currency exposure, and covenant headroom.

cashflow-forecaster

datadrivenconstruction/DDC_Skills_for_AI_Agents_in_Construction

Forecast construction project cash flow. Project income and expenses, identify funding gaps, and optimize payment timing for improved financial management.

cassandra

TerminalSkills/skills

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cassette-video-edit

Cassette-Editor/oh-my-cassette

Edit project media through the local Oh My Cassette MCP tools in Codex or Claude — a direct multi-turn conversation with the Cassette agent, with timeline previews, guided questions, and explicit export.

cast

simota/agent-skills

Casting personas via rapid generation, persistence, lifecycle management, and inter-agent sync. Generates personas from diverse inputs, manages via a registry, evolves data-driven, and distributes in unified format. Use when creating, updating, or syncing personas across agents. Not for UI walkthroughs (Echo) or user research design (Field).

castingwords-automation

ComposioHQ/awesome-claude-skills

"Automate Castingwords tasks via Rube MCP (Composio). Always search tools first for current schemas."

catalog

jongwony/epistemic-protocols

Protocol handbook — instant reference for when to use each epistemic protocol.

catalog-documentation-creator

foxminchan/BookWorm

Generates EventCatalog documentation files (services, agents, events, commands, queries, domains, flows, channels, containers) with correct frontmatter, folder structure, and best practices. Use when user asks to "document a service", "document an agent", "document an AI agent", "create EventCatalog files", "add an event to the catalog", "document my architecture", "generate catalog documentation", "create documentation for my microservice", or "document a database".

catalog-items

serac-labs/serac

Build ServiceNow Service Catalog items, variables, variable sets, catalog client scripts, record producers, and order guides with reference qualifiers and dynamic pricing.

catalog-listings

anthropics/commerce-agents

Creating and improving listing content, covering titles, descriptions, attribute completeness, categorization fixes, image callouts written as text, edits written from material the operator supplies, and content-quality audits and bulk fixes across many listings. Not needed for questions about how a listing is performing.

openai/catalyst-calendar

openai/plugins

Use when building public-equity-investing catalyst calendars. Do not use for full event underwriting; use event-driven-analyzer.

anthropics/catalyst-calendar

anthropics/financial-services

Build and maintain a calendar of upcoming catalysts across a coverage universe — earnings dates, conferences, product launches, regulatory decisions, and macro events. Helps prioritize attention and position ahead of events. Triggers on "catalyst calendar", "upcoming events", "what's coming up", "earnings calendar", "event calendar", or "catalyst tracker".

catc-client-ops

automateyournetwork/netclaw

Catalyst Center client operations and monitoring - list/filter wired and wireless clients, detailed client lookup by MAC, client count analytics, time-based analysis, SSID and band filtering, wireless troubleshooting. Use when looking up a client by MAC or IP, counting clients per site or SSID, analyzing wireless band distribution, or investigating Wi-Fi signal issues.

catc-inventory

automateyournetwork/netclaw

Catalyst Center device inventory and site management - list/filter devices by hostname, IP, platform, family, role, reachability; view site hierarchy; get interface details per device; device reachability monitoring; cross-reference with pyATS. Use when listing network devices, checking device reachability, auditing software versions, viewing site hierarchy, or finding a device by serial number.

catc-troubleshoot

automateyournetwork/netclaw

Catalyst Center troubleshooting workflows - device unreachable investigation, client connectivity issues, interface down analysis, site-wide outage triage, wireless roaming problems, integration with pyATS for CLI-level diagnostics. Use when a device is unreachable, a user reports connectivity problems, an interface is down, a site has an outage, or wireless clients have roaming issues.

catchtable-sniper

NomaDamas/k-skill

Monitor Catchtable for open reservation slots and attempt booking using a logged-in Chrome session.

catchup

oliver-kriska/claude-elixir-phoenix

Summarize and review what changed while you were away. Use after a weekend, vacation, or flight to check missed PRs, git commits, Linear tickets, and meetings — one prioritized brief, not a firehose.

categorize-papers

yogsoth-ai/de-anthropocentric-research-engine

Cluster papers by theme, method, or timeline. Produces natural groupings from a paper collection. Used by scoping-survey and narrative-review.

categorizing-bsky-accounts

oaustegard/claude-skills

Analyze and categorize Bluesky accounts by topic using keyword extraction. Use when users mention Bluesky account analysis, following/follower lists, topic discovery, account curation, or network analysis.

category-allocation-best-response

lyndonkl/claude

Computes the best-response allocation of roster resources across categories in a Head-to-Head Categories matchup. Given our per-category capacity, the opponent's projected output, per-category win probabilities (from matchup-win-probability-sim), and a K-of-N winning threshold, classifies categories into pushed / contested / conceded buckets, emits per-category leverage weights for downstream lineup and streaming decisions, computes the resulting K-of-N win probability, and writes a plain-English rationale. Domain-neutral — portable to any fantasy sport with H2H Cats scoring (MLB 10-cat, NBA 9-cat, NHL 10-cat). Use when you need push/punt decisions, dominated-strategy elimination, leverage weights per cat, or best-response allocation; or when the user mentions "category allocation", "push or punt", "K of N cats", "dominated strategy elimination", "best response allocation", "Blotto fantasy", "leverage weights per cat", or "which cats to push".

category-design

guia-matthieu/clawfu-skills

"Become the Category King by creating new markets instead of competing in existing ones Use when: **Launching a company or product** that doesn't fit cleanly into existing categories; **Stuck in commodity competition** where you're compared feature-to-feature with competitors; **Redefining your market position** when \"better\" isn't working as a strategy; **Planning a major market announcement** or product launch; **Escaping price pressure** by creating net new demand instead of fighting for ex..."

category-narrative-mapper

aaron-he-zhu/aaron-marketing-skills

Use when the user asks to "map the category narrative", "tear down how competitors tell their story", or "find the language conventions in our market"; produces a category narrative map — the dominant stories and points of view in the category, its language conventions and framing clichés, and a per-competitor narrative teardown (arc, claimed onlyness, proof pattern) plus how each rival''s messaging has shifted over time (scraped copy vs archived copy). Not for the positioning canvas itself — use positioning-mapper; not for the beachhead''s beliefs and objections — use audience-belief-mapper; not for SERP keyword targeting — use keyword-research; not for claim adjudication — use offer-claims-registry. 品类叙事/竞争叙事拆解/语言惯例/叙事演变

category-page-generator

kostja94/marketing-skills

When the user wants to create, optimize, or audit e-commerce category pages or listing pages. Also use when the user mentions "category page," "product category," "faceted navigation," "filter URLs," "e-commerce listing," "category SEO," "category structure," "product filters," or "listing page." For programmatic SEO at scale, use programmatic-seo.

category-sorting

yogsoth-ai/de-anthropocentric-research-engine

Classify candidates into predefined categories using ELECTRE-Tri, FlowSort, AHPSort, or DRSA methods.

cats-automation

ComposioHQ/awesome-claude-skills

"Automate Cats tasks via Rube MCP (Composio). Always search tools first for current schemas."

cattown

BankrBot/skills

Interact with Cat Town — a Farcaster-native game world on Base. Covers KIBBLE staking (stake, claim, unlock, unstake, leaderboard, deposit history); live world state (season, weather, time of day, weekend flag); fishing drops filtered by world state; Isabella's weekend fishing competition with live prize-pool math; Paulie's weekly fish raffle (free-ticket claim, tier-based prize pool, odds, last winners); the daily 3-item boutique with KIBBLE→USD conversion; gacha spins (async VRF pay-then-receive, 100/day cap, seasonal pools); item valuation plus batch selling via the V2 vendor (5% tax); and KIBBLE tokenomics (% burned, % staked, live APY). Use when the user mentions Cat Town, KIBBLE, Wealth & Whiskers, Jasper, Isabella, Paulie, Skipper, Theodore, Cassie, RevenueShare, fishing, gacha, raffle, boutique, vendor, prize pools, drop tables, or any read/write on the Cat Town contracts.

catwoe-analysis

yogsoth-ai/de-anthropocentric-research-engine

Apply Checkland's CATWOE analysis from a specific stakeholder perspective to reveal how the problem looks from that viewpoint.

causal-chain-tracing

yogsoth-ai/de-anthropocentric-research-engine

Trace UDE to root cause via IF...THEN...BECAUSE logic chains

causal-claim-extraction

yogsoth-ai/de-anthropocentric-research-engine

Extract all causal claims (X causes Y, X leads to Y, X enables Y) from an artifact, producing a structured list of cause-effect pairs.

causal-diagnosis

microsoft/AutoSaddler

Use before proposing a mutation to diagnose measured failures from evaluator outcomes, traces, history, and the controlling candidate surfaces.

causal-genomics-colocalization-analysis

swaruplab/operon

Test whether two or more traits share a causal variant at a locus using Bayesian colocalization (coloc.abf, coloc.susie, HyPrColoc, moloc, eCAVIAR, SMR/HEIDI, PWCoCo, SharePro). Use when integrating GWAS with eQTL/sQTL/pQTL/mQTL, distinguishing shared causal variants from LD-driven coincidence, handling allelic heterogeneity, choosing between single-causal vs multi-causal methods, picking PP.H4 thresholds, running sensitivity over p12, or harmonising summary statistics for colocalization.

causal-genomics-effector-gene-prioritization

swaruplab/operon

Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.

causal-genomics-fine-mapping

swaruplab/operon

Resolves GWAS associations to candidate causal variants and credible sets via SuSiE, susie_rss, FINEMAP, CAVIAR, DAP-G, PAINTOR, PolyFun, SuSiEx, MultiSuSiE, and FOCUS. Use when narrowing a GWAS lead SNP to a 95 percent credible set, choosing between in-sample and reference LD, calibrating non-sparse loci with SuSiE-inf or FINEMAP-inf, integrating functional priors via PolyFun, fine-mapping across ancestries with SuSiEx, diagnosing LD mismatch via estimate_s_rss and kriging_rss, handling HLA or long-range LD, or feeding credible sets into coloc.susie for colocalization.

causal-genomics-genetic-correlation

swaruplab/operon

Estimate bivariate genetic correlation (rg) between traits from GWAS summary statistics or individual-level genotypes using cross-trait LDSC, HDL, LAVA, rho-HESS, GREML-bivariate, Popcorn, and HDL-L. Use when quantifying shared genetic architecture between two traits, screening MR validity before causal inference, distinguishing global from locus-level rg, estimating trans-ancestry rg, separating partial from full causation via LCV gcp, or producing a STROBE-MR-compliant cross-trait sensitivity battery. Cross-trait LDSC intercept absorbs sample overlap and is NOT a bias; HDL is biased under sample overlap above ~5%. High rg between exposure and outcome motivates CHP-aware MR sensitivity (CAUSE, LHC-MR).

causal-genomics-genomic-sem

swaruplab/operon

Fits structural equation models to GWAS summary statistics using GenomicSEM (Grotzinger 2019), including common-factor models, confirmatory factor models, ESEM, common-factor GWAS with Q_SNP heterogeneity, multivariate Wald tests, and stratified GenomicSEM partitioned heritability. Reconciles results against MTAG multi-trait analysis. Handles sample overlap via the LDSC sampling-covariance matrix, identifies and resolves Heywood cases, and verifies model fit with CFI / RMSEA. Use when modeling latent genetic architecture across correlated traits, running multivariate GWAS on a shared factor, distinguishing factor-mediated from trait-specific SNP effects, or comparing GenomicSEM common-factor results against MTAG when both depend on accurate sampling covariance.

causal-genomics-heritability-partitioning

swaruplab/operon

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

causal-genomics-mediation-analysis

swaruplab/operon

Decompose total effects into direct and indirect paths through mediators using mediation, CMAverse 4-way, HIMA/HIMA2 high-dimensional, BAMA, two-step / MVMR mediation, or double-ML medDML. Use when testing whether a molecular phenotype (expression, methylation, protein) mediates a treatment-outcome relationship, decomposing exposure-mediator interaction via VanderWeele 4-way, screening high-dimensional EWAS mediators, or running MR-based mediation when sequential ignorability is implausible.

causal-genomics-mendelian-randomization

swaruplab/operon

Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.

causal-genomics-pleiotropy-detection

swaruplab/operon

Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger, MR-PRESSO, MR-RAPS, CAUSE, LHC-MR, LCV, MR-Clust, MR-Mix, and contamination-mixture methods. Use when validating an MR causal claim, running the STROBE-MR sensitivity battery, suspecting a shared heritable confounder, working under weak-instrument or polygenic-exposure regimes, or reconciling discordant estimates across robust methods.

causal-genomics-proteome-mr-drug-target

swaruplab/operon

Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocalization triangulation, phenome-wide on-target adverse-effect scans, cross-platform Olink/SomaScan replication, and PAV (protein-altering variant) sensitivity. Use when nominating or de-risking a drug target from plasma-proteome GWAS, mimicking pharmacological inhibition via cis-pQTL instruments, separating shared-causal from LD-confounded signal under the Schmidt 2020 cis-MR framework, screening on-target adverse phenotypes pheWAS-style, or producing publication-grade STROBE-MR plus PP.H4 evidence for a target gene.

causal-genomics-transcriptome-wide-association

swaruplab/operon

Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.

causal-inference-root-cause

lyndonkl/claude

Systematically investigates causal relationships to identify true root causes rather than correlations or symptoms. Distinguishes genuine causation from spurious associations, tests competing explanations, and designs interventions addressing underlying drivers. Use when investigating why something happened, debugging systems, analyzing failures, evaluating policy impacts, or when user mentions root cause, causal chain, confounding, spurious correlation, or asks "why did this really happen?"

causal-necessity-testing

yogsoth-ai/de-anthropocentric-research-engine

Tactic: Extract causal claims, evaluate probability of necessity (PN) and sufficiency (PS) for each, classify into necessity-sufficiency quadrants.

causal-tree-building

yogsoth-ai/de-anthropocentric-research-engine

Build logical causal trees from symptoms to root causes — list UDEs, connect causal chains, validate logic, locate root causes. Combines ishikawa-decomposition, current-reality-tree, and clr-validation SOPs.

causation-consequence

Tibsfox/gsd-skill-creator

Causal reasoning in historical analysis. Covers distinguishing immediate from underlying causes, tracing chains of causation across time scales, identifying unintended consequences, and applying counterfactual reasoning to assess causal significance. Use when analyzing why historical events occurred, evaluating the relative weight of causes, or assessing whether outcomes were inevitable or contingent.

caveman

alirezarezvani/claude-skills

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caveman-commit

HoangNguyen0403/agent-skills-standard

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caveman-compress

HoangNguyen0403/agent-skills-standard

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caveman-review

HoangNguyen0403/agent-skills-standard

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cbioportal-database

jaechang-hits/SciAgent-Skills

Cancer genomics (TCGA et al.) via cBioPortal REST API. Retrieve somatic mutations, CNAs, expression, clinical data (survival/stage/treatment) across thousands of studies. Use for TMB, oncoprints, survival analysis. For population frequencies use gnomad-database; for drug-gene interactions use opentargets-database.

cbioportal-skill

openai/plugins

Submit compact cBioPortal API requests for studies, molecular profiles, mutations, clinical data, and samples. Use when a user wants concise cBioPortal summaries

cc-agy

Dianel555/DSkills

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cc-changelog

oliver-kriska/claude-elixir-phoenix

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