Browse Skills — Page 63

client-scripts

serac-labs/serac

Write ServiceNow client scripts (onLoad/onChange/onSubmit/onCellEdit) using g_form, g_user, GlideAjax, field visibility/mandatory toggles, and validation with debounced server calls.

client-side-routing

BuilderIO/agent-native

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client-validation-document

indranilbanerjee/digital-marketing-pro

Produce the Part 5 Client Validation Document — the one true stop where unbiased v1 findings meet the client. Each finding gets ACCEPT/REJECT/EDIT/DEFER decision.

client-workspace

aAAaqwq/AGI-Super-Team

Create client folder structure in Drive, share docs, check permissions before calls

climate-science

Tibsfox/gsd-skill-creator

Climate physics, forcing, feedback, and attribution. Covers the greenhouse effect and radiative forcing, climate sensitivity, fast and slow feedbacks, the paleoclimate record, detection and attribution science, regional climate impacts, and the distinction between weather, climate variability, and forced climate change. Use when reasoning about global warming mechanisms, interpreting temperature or CO2 records, evaluating attribution claims for extreme events, or distinguishing signal from natural variability.

climate-tech-advisor

borghei/Claude-Skills

>

cline

TerminalSkills/skills

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clinic-research-design

aipoch/medical-research-skills

Generates a structured prompt framework for clinical study protocols. Supports Diagnostic, Efficacy, Etiology, and Prognosis studies. Calculates sample size and provides logic guides for LLMs.

clinic-sample-size

aipoch/medical-research-skills

Unified tool for calculating sample sizes for Diagnostic, Efficacy, Etiology, and Prognosis clinical studies. Supports various statistical methods (Sensitivity/Specificity, Log-rank, Chi-square, EPV, etc.).

clinical_pharmacology_report

InternScience/scp

Clinical Pharmacology Report - Generate clinical pharmacology report: PK, PD, mechanism, drug interactions, and special populations. Use this skill for clinical pharmacology tasks involving get pharmacokinetics by drug name get pharmacodynamics by drug name get mechanism of action by drug name get drug interactions by drug name get geriatric use info by drug name. Combines 5 tools from 1 SCP server(s).

clinical_trial_drug_profile

InternScience/scp

Clinical Trial Drug Profiling - Profile drug for clinical trials: FDA clinical studies, contraindications, pregnancy info, and geriatric use. Use this skill for clinical research tasks involving get clinical studies info by drug name get contraindications by drug name get pregnancy effects info by drug name get geriatric use info by drug name. Combines 4 tools from 1 SCP server(s).

clinical-biostatistics-adaptive-designs

swaruplab/operon

Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.

clinical-biostatistics-bayesian-trials

swaruplab/operon

Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

clinical-biostatistics-categorical-tests

swaruplab/operon

Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.

clinical-biostatistics-cdisc-data

swaruplab/operon

Reads, validates, and prepares CDISC SDTM and ADaM clinical trial data for analysis. Covers SDTM domain joins (DM, AE, EX, VS, LB, DS), ADaM architecture (ADSL, BDS, OCCDS, ADTTE) with traceability, treatment-emergent AE conventions, baseline derivation, SUPPQUAL/NSV handling, Define-XML 2.1, and Pinnacle 21 / CORE validation. Use when working with clinical trial datasets in CDISC SDTM/ADaM format, preparing analysis-ready data, or validating for regulatory submission.

clinical-biostatistics-effect-measures

swaruplab/operon

Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

clinical-biostatistics-logistic-regression

swaruplab/operon

Performs logistic regression for clinical trial outcomes (binary, ordinal, multinomial) with marginal-vs-conditional estimand reporting per FDA 2023 covariate adjustment guidance, g-computation/standardisation for marginal effects, modified Poisson for RR, Brant test for proportional odds, Firth penalty for separation, and Hauck-Donner detection. Use when modeling binary or ordinal endpoints in confirmatory or exploratory clinical trials.

clinical-biostatistics-missing-data

swaruplab/operon

Implements missing-data sensitivity analyses for confirmatory clinical trials including MMRM under MAR (with Kenward-Roger correction), reference-based multiple imputation (J2R, CR, CIR, LMCF per Carpenter-Roger 2013), Permutt delta-adjustment / tipping-point analysis, pattern-mixture identifying restrictions (CCMV, NCMV, ACMV), and the Cro vs Bartlett variance debate. Use when handling missing primary or secondary endpoint data in regulatory submissions following NRC 2010 and ICH E9(R1).

clinical-biostatistics-multiplicity-graphical

swaruplab/operon

Implements multiplicity control for confirmatory clinical trials using graphical procedures (Bretz-Maurer-Hommel), gatekeeping (parallel, serial, mixed), Hochberg/Hommel/Holm with PRDS, and the closed-testing principle (Marcus-Peritz-Gabriel; Goeman 2021 admissibility). Covers FDA Multiple Endpoints Final Guidance (October 2022), graphical procedures via R gMCP, primary + key-secondary + subgroup hierarchies, and FWER vs FDR distinction. Use when designing the multiplicity strategy for confirmatory trials with multiple primary or key secondary endpoints.

clinical-biostatistics-power-sample-size

swaruplab/operon

Computes sample size and power for clinical trials including continuous, binary, and time-to-event endpoints; superiority, non-inferiority, and equivalence designs; FDA 2016 non-inferiority margin selection with M1/M2 framework; Schoenfeld 1981 and Lakatos 1988 for survival; Schuirmann TOST and 80-125% bioequivalence; minimum clinically important difference (MCID) vs δ distinction. Use when justifying trial size in protocol or SAP per CONSORT 2025 item 7.

clinical-biostatistics-subgroup-analysis

swaruplab/operon

Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.

clinical-biostatistics-survival-analysis

swaruplab/operon

Performs time-to-event analysis for clinical trials including Cox proportional hazards regression with PH diagnostics, restricted mean survival time (RMST) under non-PH, competing risks via Fine-Gray vs cause-specific Cox, weighted log-rank and MaxCombo for non-proportional hazards, recurrent events (Andersen-Gill, PWP, WLW), and interval-censored data. Use when analyzing time-to-event endpoints (OS, PFS, DOR, TTR, TTNT) in oncology or other clinical trials.

clinical-biostatistics-trial-reporting

swaruplab/operon

Prepares statistical reports for clinical trials following CONSORT 2025, SPIRIT 2025, ICH E9(R1) estimands, and FDA 2023 covariate adjustment guidance. Covers Table 1 generation, analysis populations (ITT/FAS/PP/Safety), the 5 ICH E9(R1) intercurrent-event strategies, MMRM under MAR (mmrm), reference-based MI (rbmi J2R/CR/CIR), Permutt tipping-point sensitivity, and Rubin's-rules vs frequentist variance debate. Use when preparing regulatory submissions, defining estimands, or implementing missing-data sensitivity analyses.

clinical-case-summary

mohitagw15856/pm-claude-skills

Write a structured clinical case summary or case presentation. Use when asked to write a clinical case summary, case presentation, patient case report, or clinical handover. Produces a structured summary using SBAR or SOAP format. For educational and documentation purposes only — not a substitute for clinical judgement.

clinical-cohort-protocol-designer

aipoch/medical-research-skills

Designs retrospective or prospective clinical cohort study protocols for biomedical and clinical research. Always use this skill when the user needs a cohort-based study plan rather than a general study idea, evidence summary, or mechanistic experiment design. Focus on cohort appropriateness, enrollment logic, baseline time-zero definition, follow-up structure, endpoint definition, variable collection, confounding control, and a coherent primary statistical analysis line. Do not invent data availability, follow-up completeness, outcome ascertainment quality, sample size adequacy, or causal interpretability.

clinical-data-cleaner

aipoch/medical-research-skills

Use when cleaning clinical trial data, preparing data for FDA/EMA submission, standardizing SDTM datasets, handling missing values in clinical studies, detecting outliers in lab results, or converting raw CRF data to CDISC format. Cleans and standardizes clinical trial data for regulatory compliance with audit trails.

clinical-decision-support

K-Dense-AI/scientific-agent-skills

Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.

clinical-decision-support-documents

jaechang-hits/SciAgent-Skills

Guidelines for clinical decision support (CDS) documents: biomarker-stratified cohort analyses and GRADE-graded treatment reports. Covers structure, executive summaries, evidence grading (1A–2C), stats (HR, CI, survival), and biomarker integration. Use for pharma research docs, clinical guidelines, regulatory submissions.

clinical-diagnostic-reasoning

swaruplab/operon

Identify and counteract cognitive biases in medical decision-making through systematic error analysis and contextual algorithm application. For diagnostic reasoning, treatment decisions, and

clinical-foundations

Tibsfox/gsd-skill-creator

Foundations of clinical psychology and psychopathology. Covers anxiety disorders (generalized anxiety, panic, phobias, OCD, PTSD), depressive disorders (major depression, persistent depressive disorder, bipolar), personality theories (psychodynamic, trait/Big Five, humanistic, social-cognitive), therapeutic approaches (CBT, psychodynamic, humanistic/person-centered, behavioral, pharmacological), the biopsychosocial model, DSM diagnostic framework, and the evidence base for psychological treatments. Use when analyzing psychological disorders, therapeutic approaches, personality assessment, or the intersection of biology, psychology, and social context in mental health.

clinical-nlp-extractor

swaruplab/operon

Extracts medical entities (Diseases, Medications, Procedures) from unstructured clinical text using regex and simple rules (or LLM wrappers).

clinical-note-extract-skill

anthropics/healthcare

Extract structured data from clinical notes with span-level provenance and null-safety. Use when users say "extract [variables] from this note", "abstract this chart", "pull structured data from these notes", "what does this note say about [field]", or when building a chart-abstraction, registry, or cohort dataset from unstructured clinical text.

clinical-note-summarization

swaruplab/operon

Structure raw clinical notes into SOAP-format summaries with explicit contradictions, missing data, and ICD-linked assessments using the provided prompt + usage script.

clinical-question-clarifier

aipoch/medical-research-skills

Clarifies a vague clinical or biomedical research idea into a structured, bounded, searchable, researchable, and testable question. Always use this skill whenever a user has an early-stage clinical or research thought, an over-broad topic, an ill-defined evidence question, or an unclear problem statement that must be translated into a question framing suitable for literature retrieval, evidence synthesis, gap analysis, study design, or downstream protocol planning. Never jump straight to answering the substantive medical question unless the user explicitly asks for that. Focus first on question framing, boundary setting, and downstream-ready formulation.

clinical-reports

K-Dense-AI/scientific-agent-skills

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.

clinical-research

alirezarezvani/claude-skills

Use when designing a prospective clinical study before submission — selecting and classifying endpoints (primary / key-secondary / exploratory, with surrogate-endpoint flagging), estimating sample size and power for two-arm designs (means / proportions / survival), or scoring a study plan for feasibility and a GO / GO-WITH-CONDITIONS / REDESIGN / NO-GO phase-gate decision. Every output is an ESTIMATE plus a named human owner (clinician / biostatistician / regulatory owner) — never clinical fact, never a finished protocol. Distinct from ra-qm-team, which handles the regulatory/QM submission (ISO 13485, EU MDR, FDA 510(k)/PMA/QSR), not the study design.

clinical-study-info-extractor

aipoch/medical-research-skills

Batch extracts and verifies structured information (PMID, title, abstract, methodology, results, etc.) from clinical research literature using PMIDs. Use when the user wants to extract details from specific PMIDs.

clinical-trial-protocol-skill

anthropics/healthcare

Generate clinical trial protocols for medical devices or drugs. This skill should be used when users say "Create a clinical trial protocol", "Generate protocol for [device/drug]", "Help me design a clinical study", "Research similar trials for [intervention]", or when developing FDA submission documentation for investigational products.

clinical-trial-protocol-skill

swaruplab/operon

Generate clinical trial protocols for medical devices or drugs. This skill should be used when users say "Create a clinical trial protocol", "Generate protocol for [device/drug]", "Help me design a clinical study", "Research similar trials for [intervention]", or when developing FDA submission documentation for investigational products.

clinical-trials

mkurman/zorai

ClinicalTrials.gov API client and analysis toolkit. Search, filter, and download trial records. Analyze trial designs, endpoints, enrollment, sponsors, and results. Automate systematic trial discovery.

clinical-trials-search

swaruplab/operon

Search ClinicalTrials.gov with natural language queries. Find clinical trials, enrollment, and outcomes using Valyu semantic search.

clinicaltrials-database

swaruplab/operon

Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

clinicaltrials-database-search

jaechang-hits/SciAgent-Skills

Query ClinicalTrials.gov API v2 for trial data. Search by condition, drug/intervention, location, sponsor, or phase; fetch details by NCT ID; filter by status; paginate; export CSV. For clinical research, patient matching, and trial portfolio analysis.

clinicaltrials-db

aipoch/medical-research-skills

Query the ClinicalTrials.gov API v2 to search for clinical trials, retrieve detailed study protocols, and analyze recruitment status; use when you need to find trials by condition/drug, export results, or verify study details by NCT ID.

clinicaltrials-gov-parser

aipoch/medical-research-skills

Monitor and summarize competitor clinical trial status changes from ClinicalTrials.gov.

clinicaltrials-skill

openai/plugins

Submit compact ClinicalTrials.gov API v2 requests for study search, metadata, enums, search areas, and field statistics. Use when a user wants concise ClinicalTrials.gov summaries

clinpgx-database

jaechang-hits/SciAgent-Skills

Query the ClinPGx (formerly PharmGKB) REST API plus the CPIC PostgREST companion API for pharmacogenomic clinical annotations, CPIC/DPWG dosing guidelines, gene-drug pairs, variant-drug associations, FDA/EMA drug labels, and PGx pathways. Two-host architecture: api.clinpgx.org for annotation records, api.cpicpgx.org for genotype→recommendation lookups. No auth. For germline pathogenicity use clinvar-database; for somatic cancer PGx use cosmic-database or opentargets-database; for drug bioactivity use chembl-database-bioactivity.

clinvar-database

jaechang-hits/SciAgent-Skills

Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations. Search by gene/rsID/condition/review status; returns ClinSig, submitter data, conditions, HGVS. For GWAS use gwas-database; for variant consequence prediction use Ensembl VEP.

clinvar-variation-skill

openai/plugins

Submit compact ClinVar Clinical Tables and NCBI Variation requests for search, VCV, RCV, SCV, and RefSNP lookups. Use when a user wants variant-level summaries or identifier mapping

clip

NousResearch/hermes-agent

OpenAI's model connecting vision and language. Enables zero-shot image classification, image-text matching, and cross-modal retrieval. Trained on 400M image-text pairs. Use for image search, content moderation, or vision-language tasks without fine-tuning. Best for general-purpose image understanding.

clip-seq-ago-clip-mirna-targets

swaruplab/operon

Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.

clip-seq-binding-site-annotation

swaruplab/operon

Annotate CLIP-seq peaks or crosslink sites to RNA features (5'UTR, CDS, 3'UTR, intron, splice junction, snoRNA, tRNA, ncRNA, repeat elements) with ChIPseeker, RCAS, RBP-Maps (Yeo splicing regulatory maps), and bedtools, applying feature-priority hierarchies, transcript-context resolution, and metagene aggregation. Use when characterizing where in transcripts an RBP binds, comparing peak distribution across regions, generating splicing-regulatory maps relative to alternative-splicing events, or distinguishing exonic vs intronic vs UTR binding.

clip-seq-clip-alignment

swaruplab/operon

Align preprocessed CLIP-seq reads (eCLIP, iCLIP, iCLIP2, PAR-CLIP) to genome with STAR or bowtie2 using crosslink-preserving parameters, choosing between unique-mapper-only and multi-mapper-aware alignment for repeat-binding RBPs, deciding STAR vs HISAT2 memory trade-offs, and applying ENCODE-compatible filters. Use when turning preprocessed CLIP FASTQ into a deduplicated, MAPQ-filtered BAM ready for peak calling or crosslink-site detection.

clip-seq-clip-deep-learning

swaruplab/operon

Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.

clip-seq-clip-motif-analysis

swaruplab/operon

Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro RBNS Kd, reconciling motif disagreements across tools, or correcting for the uracil crosslinking bias that contaminates raw CLIP motif logos.

clip-seq-clip-peak-calling

swaruplab/operon

Call protein-RNA binding sites from CLIP-seq BAM with CLIPper, PureCLIP, Skipper, Piranha, omniCLIP, CTK, CLAM, or Paraclu. Use when choosing between coverage-based, HMM-based, beta-binomial window-based, and crosslink-site-based peak callers; applying ENCODE eCLIP thresholds (log2 IP/SMInput >= 3, -log10 p >= 3); deciding when SMInput is mandatory; or reconciling peak-set discordance between callers for the same RBP.

clip-seq-clip-preprocessing

swaruplab/operon

Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

clip-seq-clip-qc

swaruplab/operon

Comprehensive quality control for CLIP-seq libraries (eCLIP, iCLIP, iCLIP2, PAR-CLIP) covering library complexity (preseq), FRiP, IDR replicate reproducibility, read-distribution metagene, SMInput vs IgG control rationale, rRNA / snoRNA contamination, fragment-length distribution, and ENCODE-compliance thresholds. Use when assessing whether a CLIP library passed, deciding lenient vs stringent peak thresholds, comparing replicates with IDR rescue and self-consistency ratios, or distinguishing failed IP from over-amplified library.

clip-seq-crosslink-site-detection

swaruplab/operon

Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

clip-seq-differential-clip

swaruplab/operon

Identify differentially bound regions across CLIP-seq conditions (knockdown vs control, treatment vs vehicle, disease vs healthy) using DEWSeq (sliding-window DESeq2), Flipper (Skipper-downstream), ASpeak, edgeR, or limma-voom. Use when computing condition-level changes in RBP binding intensity, choosing peak-level vs window-level vs crosslink-level testing, designing replicate experiments, or distinguishing biological binding shifts from technical confounders.

clip-seq-m6a-clip

swaruplab/operon

Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023, antibody-free chemical conversion), DART-seq (Meyer 2019, APOBEC1-YTH fusion), m6Anet (nanopore direct RNA), or MeRIP-seq with calibration. Use when distinguishing antibody-based from antibody-free m6A detection methods, applying the DRACH motif constraint, reconciling cross-method disagreements (DART 44% in DRACH vs GLORI), or detecting m6Am at the cap.

clip-seq-stamp-antibody-free

swaruplab/operon

Profiles RNA-binding protein targets without antibody or UV crosslinking using STAMP (APOBEC1-RBP fusion, C-to-U editing), scSTAMP (single-cell), TRIBE/HyperTRIBE (ADAR-RBP, A-to-I editing), DART-seq (APOBEC1-YTH for m6A), or Bullseye/SAILOR edit-site detection pipelines. Use when antibody is unavailable or specificity is doubtful, when single-cell RBP profiling is needed (scSTAMP), or when in vivo RBP profiling without UV is preferred.

clipboard

bitwize-music-studio/claude-ai-music-skills

Copies track content (lyrics, style prompts, streaming lyrics) to the system clipboard. Use when the user needs to paste lyrics or style prompts into Suno or other external tools.

clipboard-history

taracodlabs/aiden

Read/write Windows clipboard text, HTML, images, history (PowerShell)

clipboard-testing

ClipboardHealth/core-utils

End-to-end testing playbook for Clipboard Health changes. Use when the user wants to verify, exercise, or set up test data for a backend or frontend change against a live environment — "test my change end-to-end", "verify this works in dev", "create a test workplace / worker / shift", "get a shift through to paid / invoiced", "prove the API change works". Defaults to the `development` AWS environment, API-first (cbh CLI tokens + curl). The skill knows enough to run the core happy-path flow (workplace → worker → shift → clock in/out → pay → invoice) autonomously; for anything else, it orients around the codebase and asks the user for missing directories.

clippy-configuration

TheBushidoCollective/han

Use when configuring Clippy for Rust projects with TOML config, lint groups, attributes, and workspace setup.

clippy-custom

TheBushidoCollective/han

Use when developing custom Clippy lints, implementing lint passes, and contributing to Clippy for Rust code standards.

clippy-lints

TheBushidoCollective/han

Use when applying Clippy lint categories for Rust code including correctness, performance, style, and custom lint configuration.

cloak

simota/agent-skills

Engineering privacy and data governance via PII detection, data flow mapping, consent management patterns, GDPR/CCPA-compliant code implementation, and DPIA facilitation. Use when privacy-by-design implementation is needed.

Clockify Automation

ComposioHQ/awesome-claude-skills

"Automate time tracking workflows in Clockify -- create and manage time entries, workspaces, and users through natural language commands."

clone-website

JasonxzWen/harness-hub

Load when the user explicitly asks to clone, reverse-engineer, or rebuild a website they own or are authorized to reproduce; do not load for generic redesign, inspiration, scraping, phishing, impersonation, or copying third-party brands.

cloning-project

oaustegard/claude-skills

Exports project instructions and knowledge files from the current Claude project. Use when users want to clone, copy, backup, or export a project's configuration and files.

cloning-websites-to-weaverse

Weaverse/shopify-hydrogen-skills

Use when recreating a reference website or brand hub in this Hydrogen plus Weaverse repo, especially when deciding whether to reuse sections, add global styles, update theme schema, or resolve conflicts between the live site and project brand guidelines.

close

vm0-ai/vm0-skills

Close CRM API for sales management. Use when user mentions "Close CRM",

close-automation

benjaminasterA/antigravity-awesome-skills

Automate Close CRM tasks via Rube MCP (Composio): create leads, manage calls/SMS, handle tasks, and track notes. Always search tools first for current schemas.

close-automation-v2

diegosouzapw/awesome-omni-skills

Close CRM Automation via Rube MCP workflow skill. Use this skill when the user needs Automate Close CRM tasks via Rube MCP (Composio): create leads, manage calls/SMS, handle tasks, and track notes. Always search tools first for current schemas and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.

close-case-artifact

dandye/ai-runbooks

"Close a case or alert with proper reason and documentation. Use when triage determines an alert is FP/BTP or investigation is complete. Requires artifact ID, type, closure reason, and root cause."

close-controls-and-accounting

Significant-Gravitas/skills-catalog

Use for month-end close support: the checklist with owners and status, accrual review, account reconciliations, control evidence, and audit preparation.

close-management

modu-ai/cowork-plugins

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close-management

anthropics/knowledge-work-plugins

Manage the month-end close process with task sequencing, dependencies, and status tracking. Use when planning the close calendar, tracking close progress, identifying blockers, or sequencing close activities by day.

close-month

anthropics/knowledge-work-plugins

Closes the books and turns them into a decision as a three-link chain — month-end-prep reconciles the ledger against every connected payment processor and writes the P&L narrative, cash-flow-snapshot then refreshes the 30/60/90-day forecast off the newly closed numbers rather than raw ones, and report-builder publishes and distributes the close packet. Requires a ledger (MYOB, NetSuite, QuickBooks, Xero, or Zoho Books) and uses Gusto, PayPal, Ramp, Shopify, Square, and Stripe when connected, falling back to statement or CSV uploads. Trigger on "close the month," "month-end," "close the books," "reconcile," "send the close packet to my accountant," or when the owner asks why revenue or margin moved last month. An owner who wants only the reconciliation and its flags, with no forecast refresh and no packet distribution, routes to month-end-prep directly.

close-plan

anthropics/knowledge-work-plugins

Build the business case and mutual action plan for a deal - the why-buy/why-now story, the ROI framing, and the dated step-by-step path to signature shared with the customer. Use when the user says "build a close plan for [deal]", "mutual action plan for [account]", "business case for [opp]", or "what's the path to signature".

closed-loop-delivery

diegosouzapw/awesome-omni-skills

Closed-Loop Delivery workflow skill. Use this skill when the user needs a coding task must be completed against explicit acceptance criteria with minimal user re-intervention across implementation, review feedback, deployment, and runtime verification and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.

closed-loop-delivery-v2

diegosouzapw/awesome-omni-skills

Closed-Loop Delivery workflow skill. Use this skill when the user needs a coding task must be completed against explicit acceptance criteria with minimal user re-intervention across implementation, review feedback, deployment, and runtime verification and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.

closed-won-to-cs-capacity-modeling

t0ddc3by/claude-for-customer-success

Converts rolling sales forecast into CS resource demand using UoG formulas. Runs three-scenario capacity check (P10/P50/P90 from scenario-modeling). Compares projected CSM demand to current headcount and UoG annual plan baseline. Surfaces CS capacity gaps with a hiring lead time flag. Updates when SA1 forecast moves >10%. Triggers: 'CS capacity', 'can CS absorb', 'CSM headcount needed', 'CS ceiling', 'will CS be able to handle new logos'.

closedloop-env

closedloop-ai/claude-plugins

Provides ClosedLoop environment paths (CLOSEDLOOP_WORKDIR, CLAUDE_PLUGIN_ROOT) to agents. This skill should be used by any agent that needs to access ClosedLoop run directories, plugin schemas, or other path-dependent resources.

closeout-review

trailofbits/coop

Run the final scope-controlled review before committing, pushing, or opening a PR.

closer-critique

lyndonkl/claude

Evaluates the final paragraph of a substacker draft for compression and closing form — bolded maxim, forward-looking question, or compressed mechanism statement. For series posts (frontmatter series: {slug}), verifies the running scoreboard (P&L, Brier, W-L) is present and updated. Use on every draft. Blocks publication of series posts missing the scoreboard. Trigger keywords: closer, closing, last paragraph, bolded maxim, scoreboard, CTA, wrap up, conclusion.

closest-worlds

yogsoth-ai/de-anthropocentric-research-engine

Strategy: Lewis Possible Worlds — find the minimal change to reality that would flip the conclusion, measuring how close the nearest world where the conclusion fails.

closing-checklist

anthropics/claude-for-legal

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cloth-sim

arjun988/blender-skills

Garment blockout, cloth simulation, pin groups, and bake to shape keys or caches for characters and props in Blender via MCP.

cloud

browser-use/browser-use

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Cloud Security & Container Hardening

Masriyan/Claude-Code-CyberSecurity-Skill

AWS/Azure/GCP security auditing, container and Kubernetes hardening, Infrastructure as Code scanning, and cloud compliance assessment

cloud-act-und-drittstaat-pruefen

Klotzkette/claude-fuer-deutsches-recht

Pruefe Auslandsbezug des KI-Anbieters nach Absatz vier der einschlaegigen Dienstleisterregelung (BRAO StBerG WPO PAO BNotO). EU/EWR werden als gleichwertig unterstellt. Drittstaaten benoetigen vergleichbares Schutzniveau. US-CLOUD Act und Foreign Intelligence Surveillance Act schaffen Restzugriff. Professional Secrecy Addendum empfohlen. DAV-Stellungnahme Seite fuenfzehn sechzehn.

cloud-adoption

MicrosoftDocs/cloud-adoption-framework

How to adopt and integrate the Microsoft Azure cloud into your organization. Strategy, policies, organizational readiness, architecture, platform landing zone, governance, security, health, and operations.

cloud-aksk-exploit

wgpsec/AboutSecurity

云凭据(AK/SK)泄露后的完整利用链。当通过信息泄露/.env文件/git泄露/SSRF元数据获取到云平台 Access Key 和 Secret Key 后使用。当获取到 AWS AKIA*/ASIA*、腾讯云 AKIDz*、阿里云 LTAI* 等凭据格式时使用。覆盖凭据配置→权限枚举→资源接管→后门持久化的完整攻击链。与 cloud-iam-audit（侧重策略分析）互补——本 skill 侧重拿到凭据后的实战利用动作。腾讯云比赛场景的 CAM/COS/CVM/SCF 利用是重点。发现任何云 API 密钥、临时凭据、或 STS Token 时都应使用此 skill

cloud-architect

Jeffallan/claude-skills

Designs cloud architectures, creates migration plans, generates cost optimization recommendations, and produces disaster recovery strategies across AWS, Azure, and GCP. Use when designing cloud architectures, planning migrations, or optimizing multi-cloud deployments. Invoke for Well-Architected Framework, cost optimization, disaster recovery, landing zones, security architecture, serverless design.

cloud-architect-v2

diegosouzapw/awesome-omni-skills

cloud-architect workflow skill. Use this skill when the user needs Expert cloud architect specializing in AWS/Azure/GCP multi-cloud infrastructure design, advanced IaC (Terraform/OpenTofu/CDK), FinOps cost optimization, and modern architectural patterns and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.

cloud-commit-and-marketplace-selling

Significant-Gravitas/skills-catalog

Use when a deal involves a cloud consumption commit, a marketplace private offer, or a multi-year enterprise agreement.

cloud-design-patterns

github/awesome-copilot

'Cloud design patterns for distributed systems architecture covering 42 industry-standard patterns across reliability, performance, messaging, security, and deployment categories. Use when designing, reviewing, or implementing distributed system architectures.'